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South-America River and Sea Cruises.

South America is full of nature with clear highlights: a) the Amazon River Basin aka “the lungs of the world”, b) the Andes Mountains, the highest peaks outside of the Himalayas and c) wild Patagonia. Most people speak either Spanish or Portuguese, everyone likes music and dance.

Search and compare River and Sea Cruises in South-America. Book at the tour operator.

We have 1006 tour operators that conduct 106 cruises in South-America with duration starting at USD 5,943.

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Coming from:
United States
Languages:
English
Continent:
South-America
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  • English English (25)
  • ship Ships (Vessels) (6)

Operators with widest selection (sample tours)

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Antarctic Marine Mammals: The World of Whales and Seals (Quark)Google Map: Antarctic Marine Mammals: The World of Whales and Seals

1/11 Antarctic Marine Mammals: The World of Whales and Seals

preview
Sea Cruise

Imagine sitting in a Zodiac or kayak in the waters off the Antarctic Peninsula in the company of marine mammal scientists, listening to whale sounds—sometimes haunting, sometimes melodic—from deep beneath the ocean surface. You, the guest, aren’t merely a...

From/To
Buenos Aires (Round Trip)
Ports of call
Buenos Aires, Ushuaia, Drake Passage, Antarctic Peninsula, Cuverville Island, South Shetland Islands
Travel Quality
Luxury Tour
Operator
Ship
World Voyager
Duration
11 Days
Starting at
USD 14,200
Operator
-29.4%

Starting at

USD 14,200

USD 10,000

11 Days
Next Departure
05-Mar-2027
 
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Realm of Penguins & Icebergs (Poseidon)Google Map: Realm of Penguins & Icebergs

1/7 Realm of Penguins & Icebergs

preview
Sea Cruise

Expedition Cruise on M/v Sea Spirit to Classic Antarctica .

From/To
Ushuaia (Round Trip)
Ports of call
Ushuaia, Drake Passage, South Shetland Islands, Antarctic Peninsula
Travel Quality
Luxury Tour
Operator
Ship
M/v Sea Spirit
Duration
12 Days
Starting at
USD 15,600
Operator

Starting at

USD 15,600

12 Days
Next Departure
28-Nov-2026
 
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Along the Amazon and the Rio Negro, An Exclusive Cruise through Pristine and Hidden Nature (port-to-port cruise) (Croisi Voyages)

1/5 Along the Amazon and the Rio Negro, An Exclusive Cruise through Pristine and Hidden Nature (port-to-port cruise)

preview
River Cruise

Where the forest knows no borders, where thousands of plant and animal species coexist to form a one-of-a-kind ecosystem, where the soft morning light reveals lush and colorful landscapes, and where nightfall brings with it mystical sounds open to interpr...

From/To
Manaus (Round Trip)
Operator
Ship
RV Brasilian Dream NEW
Duration
11 Days
Starting at
± USD 5,943
Operator

Starting at

± USD 5,943

11 Days
Next Departure
20-Feb-2027
04-Mar-2027
 
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From the Inca Empire to the Peruvian Amazon with Galápagos Cruise (Avalon)Google Map: From the Inca Empire to the Peruvian Amazon with Galápagos Cruise

1/2 From the Inca Empire to the Peruvian Amazon with Galápagos Cruise

preview
River Cruise

Experience the archaeological treasures and scenic beauty of Peru with the fascinating untamed rainforest of the Amazon and the stunning marine life and tropical waters of the Galápagos Islands. This amazing river cruise vacation offers a little something...

From/To
Lima ⇒ Quito
Ports of call
Lima, Sacred Valley of the Incas, Cusco, Sacsayhuamán, Ollantaytambo, Machu Picchu, Santo Domingo, I...
Operator
Ship
Delfin III
Duration
18 Days
Starting at
USD 15,500
Operator
-4.8%

Starting at

USD 15,500

USD 14,800

18 Days
Next Departure
12-Apr-2026
10-May-2026