The Serengeti is the largest area in the world where lions, giraffe, elephants, rhino, zebra, gnu and many other animals run around in their natural habitat. The plains are mostly wide-open and safaris are the most common activity. The Serengeti is partly in Tanzania, partly in Kenya - but animals don´t need passports to cross the border for their endless migration...
The Kruger National Park is one of the largest game reserves in the world. The big five and many other animals have their home here. The location north-east of Johannesburg makes it an easy destination.
The Ngorongoro Crater is one of those places in Africa where you can find all wildlife - including the Big Five - on a very small area. And they will stay there till you visit as well, because they are "trapped" in a large volcano crater with steep walls around them...
Chobe National Park is Botswana's first national park, and also the most biologically diverse. It has one of the greatest concentrations of game in all of Africa.
Okavango is a unique National Park with land- and water- wildlife. It is like a giant oasis in the middle of deserts. Don´t miss the crocodiles and hippopothamus from a canoe... Note that a river delta that ends in a desert and not in an ocean or sea is unique all by itself!
The Masai Mara National Reserve is one of the main national parks in Kenya (and Africa) with a lot of wildlife. It borders the Serengeti National Park in Tanzania.
Etosha is a major national park with wild animals in Namibia. You can find the Big Five here, plus an abundance of desert live.
Amboseli is a great national park with superb wildlife. The excellent view of Mt. Kilimanjaro from the park make it one of the best safari experiences in Africa.