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Tours & Trips between Mexico and Panama.

Visit destinations like Chichén Itzá, Playa del Carmen, Carmen (Mexico) & Panama City, Colon, Tocumen (Panama).

Mexico is the 3rd major country on the North-American continent and the only one where Spanish is the first language. Mexico-for-tourists is known for Maya ruins, beaches, excellent food, Mariachi music and great weather. Mexico city is one of the largest cities on the planet.

Panama

Panama
Panama is a modern tropical country best known for the Panama Canal that connects the Atlantic and Pacific Oceans. But there is more: Rain Forests, Beaches and the San Blas Islands make for a great trip. Crossing the Darien Gap may not be for everyone... Panama may surpass Costa Rica in annual visitors.

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Top Destinations in Mexico.

Below are our most visited cities, destinations and national parks in Mexico. Click on the city for more details of the destination.

Chichén Itzá

Chichén Itzá (5)

Chichén Itzá is probably the most famous archeological site in Mexico and North America. About 1000-1500 years ago it was one of the largest Mayan cities and surrounded by myths and religious beliefs, The site features different architectural styles. "El Castillo" (the castle) was the way to the Sun and is still one of the most famous buildings.

Playa del Carmen

Playa del Carmen (5)

Playa del Carmen is located on the Riviera Maya very close to Cancun with lots of hotels, restaurants and tourists. The water is clean and great for swimming, snorkeling and diving.

Cancun

Cancun (3)

Cancun and Playa del Carmen are famous beach resorts on the Riviera Maya with the best hotels, bars and a lot of US-Americans.

Teotihuacán

Teotihuacán (3)

Teotihuacán is an ancient city north of Mexico City. Today it is mainly known for the large Pyramid of the Sun and the Pyramid of the Moon. Long ago Teotihuacan was the largest city in the Americas, believed a religious centre.

Mexico City

Mexico City (2)

Mexico City is one of the largest and busiest cities in the world. It is the heart of the country and center for everything modern and traditional for the rich and the poor. Visit for example the Zocalo and have some really nice food.

Oaxaca

Oaxaca (2)

Oaxaca is a culturally very rich, but touristy city in central Mexico. It’s known for its colonial buildings, many of which are made from green volcanic stone. There are also many colorful murals.

Palenque

Palenque (2)

Palenque features some very ancient and well-maintained Aztec ruins.

San Cristobal De Las Casas

San Cristobal De Las Casas (2)

San Cristóbal de las Casas is a town in the Central Highlands region of Chiapas. The city, especially the historic center, has maintained its Spanish colonial layout, with narrow cobblestone streets, roofs covered in red clay tile and wrought iron balconies with flowers.

 

Search and compare Tours & Trips between Mexico and Panama. Book at the tour operator.

We have 2 tour operators that conduct 5 group tours and private tours between Mexico and Panama with duration 43 - 59 Days and rates starting at USD 4,310.

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Mexico, Panama
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  • globe International Operators (5)

All 5 International Tours and Cruises

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Panama City to Cancun Travel Pass (Bamba)Google Map: Panama City to Cancun Travel Pass

Panama City to Cancun Travel Pass

preview
Group Tour

Explore vibrant Panama City and stunning Cancun with Bamba’s unforgettable travel pass. Dive into crystal-clear cenotes, roam ancient Mayan ruins, and relax on pristine beaches. Experience vibrant local culture, indulge in delicious cuisine, and witness breathtaking Caribbean sunsets. Perfect for ad...

From/To
Panama City ⇒ Cancun
Countries (9)
America, Belize, Costa Rica, France, Guatemala, Honduras, Mexico, Nicaragua, Panama
Operator
Activities
tour category: Fishingtour category: Divingtour category: Boattour category: Some bicycling is possibletour category: Walkingtour category: Naturetour category: Cookingtour category: Safari
Duration
43 Days
Starting at
USD 4,310
Operator

Starting at

USD 4,310

43 Days
Next Departure
01-Jan-2026
01-Jan-2027
Add to Favorites
Cancun to Panama City Travel Pass (Bamba)Google Map: Cancun to Panama City Travel Pass

Cancun to Panama City Travel Pass

preview
Group Tour

Embark on an unforgettable Central American adventure, exploring pristine beaches, vibrant cities, and lush jungles. This travel pass takes you from Cancun to Panama City, offering immersive experiences like snorkeling in Belize’s Blue Hole, discovering Mayan ruins in Guatemala, and hiking Costa Ric...

From/To
Chichén Itzá ⇒ Panama City
Countries (9)
America, Belize, Costa Rica, France, Guatemala, Honduras, Mexico, Nicaragua, Panama
Operator
Activities
tour category: Fishingtour category: Divingtour category: Boattour category: Some bicycling is possibletour category: Walkingtour category: Naturetour category: Cookingtour category: Safari
Duration
48 Days
Starting at
USD 4,784
Operator

Starting at

USD 4,784

48 Days
Next Departure
02-Jan-2026
 
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Mexico City to Panama City Travel Pass (Bamba)Google Map: Mexico City to Panama City Travel Pass

Mexico City to Panama City Travel Pass

preview
Group Tour

Discover the ultimate adventure from Mexico City to Panama City with this travel pass, offering a thrilling journey through Central America's cultural and natural wonders. Explore ancient Mayan ruins, lush rainforests, stunning beaches, and vibrant cities. Experience authentic local cuisine, breatht...

From/To
Teotihuacán ⇒ Panama City
Countries (9)
America, Belize, Costa Rica, France, Guatemala, Honduras, Mexico, Nicaragua, Panama
Operator
Activities
tour category: Fishingtour category: Divingtour category: Boattour category: Some bicycling is possibletour category: Walkingtour category: Naturetour category: Cookingtour category: Safari
Duration
57 Days
Starting at
USD 6,692
Operator

Starting at

USD 6,692

57 Days
Next Departure
02-Jan-2026
01-Jan-2027
Add to Favorites
Best of Central America (Intrepid)Google Map: Best of Central America

Best of Central America

preview
Group Tour

Explore incredible worlds above and below the water through some of Central America's best on this 45-day adventure. Amble down the Yucatan Peninsula to the island paradise of Caye Caulker, then cut inland to the lush jungle around Tikal, cruise to the wide river Rio Dulce and end up among the cloud...

From/To
Carmen ⇒ Panama City
Countries (7)
Belize, Costa Rica, Guatemala, Honduras, Mexico, Nicaragua, Panama
Operator
Activities
tour category: Fishingtour category: Divingtour category: Boattour category: Kayaktour category: Some bicycling is possibletour category: Walkingtour category: Naturetour category: Cookingtour category: Safari
Duration
45 Days
Starting at
USD 7,395
Operator
-15%

Starting at

USD 7,395

USD 6,286

45 Days
Next Departure
28-Feb-2026
11-Mar-2026
 
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Ultimate Central America (Intrepid)Google Map: Ultimate Central America

Ultimate Central America

preview
Group Tour

Embark on an in-depth, 59-day Central American adventure from Mexico’s capital to the home of the Panama Canal. Pass through Mexico, Belize, Guatemala, El Salvador, Honduras, Nicaragua, Costa Rica and Panama on a small-group journey through remote villages, historic cities, ancient Maya and Aztec ru...

From/To
Mexico City ⇒ Panama City
Countries (7)
Belize, Costa Rica, Guatemala, Honduras, Mexico, Nicaragua, Panama
Operator
Activities
tour category: Fishingtour category: Divingtour category: Boattour category: Kayaktour category: Some bicycling is possibletour category: Walkingtour category: Naturetour category: Cookingtour category: Safari
Duration
59 Days
Starting at
USD 10,200
Operator
-15%

Starting at

USD 10,200

USD 8,636

59 Days
Next Departure
25-Feb-2026
07-Mar-2026