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Tours & Trips between Nicaragua and Panama.

Visit destinations like Granada, Leon, Managua (Nicaragua) & Panama City, Colon, Tocumen (Panama).

Nicaragua, with capital Managua, is a Spanish-speaking country in Central America. It was re-discovered by Christopher Columbus in 1502 and since then Europeans left many traces. "Mestizos", children of locals and Europeans, were a result of these encounters. Nicaragua also has volcanos with a lot of national parks.

Panama

About Panama
Panama is a modern tropical country best known for the Panama Canal that connects the Atlantic and Pacific Oceans. But there is more: Rain Forests, Beaches and the San Blas Islands make for a great trip. Crossing the Darien Gap may not be for everyone... Panama may surpass Costa Rica in annual visitors.

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Search and compare Tours & Trips between Nicaragua and Panama. Book at the tour operator.

We have 4 tour operators that conduct 14 group tours and private tours between Nicaragua and Panama with duration 14 - 62 Days and rates starting at USD 4,029.

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globe International Operators
 
Duration
 
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Days
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Coming from:
United States
Languages:
English
Must see countries:
Nicaragua, Panama
  • globe International Operators (12)

All 11 International Tours and Cruises

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Google Map: Panama City to Antigua Travel Pass

Panama City to Antigua Travel Pass

preview
From/To
Panama City ⇒ Guatemala City
Countries (7)
America, Costa Rica, France, Guatemala, Honduras, Nicaragua, Panama
Operator
Bamba Travel
Tour Type
Group Tours Group Tours
Activities
tour category: Fishingtour category: Divingtour category: Boattour category: Walkingtour category: Naturetour category: Cookingtour category: Safari
Duration
36 Days
Starting at
USD 4,029
Operator
Bamba

Starting at

USD 4,029

36 Days
Next Departure
01-Jan-2026
01-Jan-2027
Details
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Google Map: Panama City to Mexico Maya Express Pass

Panama City to Mexico Maya Express Pass

preview
From/To
Panama City ⇒ Cancun
Countries (7)
America, Belize, Costa Rica, Guatemala, Mexico, Nicaragua, Panama
Operator
Bamba Travel
Tour Type
Group Tours Group Tours
Activities
tour category: Fishingtour category: Divingtour category: Boattour category: Some bicycling is possibletour category: Walkingtour category: Naturetour category: Cookingtour category: Safari

Tour Variations:

☛
Panama City to Cancun Travel Pass (43 Days)
Duration
40 Days
Starting at
USD 4,070
Operator
Bamba

Starting at

USD 4,070

40 Days
Next Departure
02-Jan-2026
01-Jan-2027
Details
 
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Google Map: Antigua to Panama City Travel Pass

Antigua to Panama City Travel Pass

preview
From/To
Antigua Guatemala ⇒ Panama City
Countries (7)
America, Costa Rica, France, Guatemala, Honduras, Nicaragua, Panama
Operator
Bamba Travel
Tour Type
Group Tours Group Tours
Activities
tour category: Fishingtour category: Divingtour category: Boattour category: Walkingtour category: Naturetour category: Cookingtour category: Safari
Duration
35 Days
Starting at
USD 4,092
Operator
Bamba

Starting at

USD 4,092

35 Days
Next Departure
01-Jan-2026
01-Jan-2027
Details
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Google Map: Amazing Central America

Amazing Central America

preview
From/To
Antigua Guatemala ⇒ Panama City
Countries (5)
Costa Rica, Guatemala, Honduras, Nicaragua, Panama
Operator
Intrepid Travel
Tour Type
Group Tours Group Tours
Activities
tour category: Fishingtour category: Divingtour category: Boattour category: Kayaktour category: Some bicycling is possibletour category: Walkingtour category: Naturetour category: Cookingtour category: Safari
Duration
27 Days
Starting at
USD 4,350
Operator
Intrepid

Starting at

USD 4,350

27 Days
Next Departure
05-Jul-2026
19-Jul-20263
Details
 
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Google Map: Cancun to Panama City Travel Pass

Cancun to Panama City Travel Pass

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From/To
Chichén Itzá ⇒ Panama City
Countries (9)
America, Belize, Costa Rica, France, Guatemala, Honduras, Mexico, Nicaragua, Panama
Operator
Bamba Travel
Tour Type
Group Tours Group Tours
Activities
tour category: Fishingtour category: Divingtour category: Boattour category: Some bicycling is possibletour category: Walkingtour category: Naturetour category: Cookingtour category: Safari
Duration
48 Days
Starting at
USD 4,541
Operator
Bamba

Starting at

USD 4,541

48 Days
Next Departure
02-Jan-2026
01-Jan-2027
Details
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Google Map: Cycle Nicaragua to the Panama Canal

Cycle Nicaragua to the Panama Canal

preview
From/To
Granada ⇒ Tocumen
Countries (3)
Costa Rica, Nicaragua, Panama
Operator
Explore!
Tour Type
Group Tours Group Tours
Activities
tour category: Fishingtour category: Divingtour category: Boattour category: Some bicycling is possibletour category: Safari
Duration
14 Days
Starting at
± USD 4,578
Operator
Explore!

Starting at

± USD 4,578

14 Days
Next Departure
03-Oct-2026
07-Nov-2026
Details
 
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Google Map: Mexico City to Panama City Travel Pass

Mexico City to Panama City Travel Pass

preview
From/To
Mexico City ⇒ Panama City
Countries (9)
America, Belize, Costa Rica, France, Guatemala, Honduras, Mexico, Nicaragua, Panama
Operator
Bamba Travel
Tour Type
Group Tours Group Tours
Activities
tour category: Fishingtour category: Divingtour category: Boattour category: Some bicycling is possibletour category: Walkingtour category: Naturetour category: Cookingtour category: Safari
Duration
57 Days
Starting at
USD 5,231
Operator
Bamba

Starting at

USD 5,231

57 Days
Next Departure
02-Jan-2026
01-Jan-2027
Details
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Google Map: Central American Explorer

Central American Explorer

preview
From/To
Panama City ⇒ Guatemala City
Countries (5)
Costa Rica, Guatemala, Honduras, Nicaragua, Panama
Operator
Explore!
Tour Type
Group Tours Group Tours
Activities
tour category: Horsetour category: Divingtour category: Boattour category: Some bicycling is possibletour category: Walkingtour category: Naturetour category: Safari
Duration
25 Days
Starting at
± USD 6,149
Operator
Explore!

Starting at

± USD 6,149

25 Days
Next Departure
11-Nov-20262
Details
 
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Google Map: Total Central America: Two Months of Wild

Total Central America: Two Months of Wild

preview
From/To
Panama City (Round Trip)
Countries (7)
Belize, Costa Rica, Guatemala, Honduras, Mexico, Nicaragua, Panama
Age Group
18 - 39 Years
Participants
Tours for Young Adults
Operator
G Adventures
Tour Type
Group Tours Group Tours
Activities
tour category: Divingtour category: Boattour category: Kayaktour category: Some bicycling is possibletour category: Walkingtour category: Naturetour category: Safari
Duration
62 Days
Starting at
USD 6,199
Operator
G Adventures

Starting at

USD 6,199

62 Days
Next Departure
23-Aug-20264+
29-Nov-20264+
Details
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Google Map: Best of Central America

Best of Central America

preview
From/To
Carmen ⇒ Panama City
Countries (7)
Belize, Costa Rica, Guatemala, Honduras, Mexico, Nicaragua, Panama
Operator
Intrepid Travel
Tour Type
Group Tours Group Tours
Activities
tour category: Fishingtour category: Divingtour category: Boattour category: Kayaktour category: Some bicycling is possibletour category: Walkingtour category: Naturetour category: Cookingtour category: Safari
Duration
45 Days
Starting at
USD 7,395
Operator
Intrepid

Starting at

USD 7,395

45 Days
Next Departure
18-Jul-2026
01-Aug-20262
Details